PCT is more sensitive than CRP so is a better marker for sepsis. Procalcitonin levels are only used for pneumonia and sepsis. It is also lowered in conditions where your body has lower protein levels - for example, in some liver or kidney diseases. Some conditions lower the ESR - for example, heart failure, polycythaemia and sickle-cell anaemia.
Crohn's disease (inflammatory bowel disease).Some cancers - for example, myeloma and Hodgkin's lymphoma.Various muscular and connective tissue disorders that have chronic inflammation as a feature - for example, polymyalgia rheumatica, giant cell arteritis or systemic lupus erythematosus.Certain infections (mainly bacterial infections).PV, however, is more sensitive and more specific than either ESR or CRP when monitoring the activity of rheumatoid arthritis.ĮSR, CRP and PV can be raised in many inflammatory conditions - for example: CRP is not affected by as many other factors as the PV or ESR, making it a better marker of some types of inflammation. Generally, PV and ESR do not change as rapidly as CRP does, either at the start of inflammation or as it goes away. Raised ESR, CRP and PV levels are all markers of inflammation. What conditions affect the erythrocyte sedimentation rate and C-reactive protein level?
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